of Metabolites Produced by Neisseria gonorrhea Determination of Anti-microbial Activity and Characterization



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اخلاص محمد علي الشريفي
17/03/2019 19:10:53

Neisseria gonorrhoeae, also known as gonococci, or gonococcus, is a species of gram-negative coffee beanshaped
diplococci bacteria responsible for the sexually transmitted infection gonorrhea. The objectives
of this study were analysis of the secondary metabolite products and evaluation antimicrobial activity.
Thirty nine bioactive compounds were identified in the methanolic extract of Neisseria gonorrhea. GCMS
analysis of Neisseria gonorrhea revealed the existence of the Butanoic acid , 2-methyl, Propane , 2-
methoxy, Hexanoic acid, 2-methyl, 1-Propaneamine, 3-(methylthio), 7-Methylenebicyclo[3.2.0]hept-3-
en-2-one, 1,2-Benzisothiazol-3-amine tbdms, Propanoic acid, Benzeneethanamine , N-methyl, Phenelzine,
Hexanediamide, N,N’-di-benzoyloxy, Benzeneacetic acid, Silane, methylenebis, Ethanamine, N-ethyl- N-
[(1-methylethoxy)methyl], 2-Pentanamine, Butanal, 4-hydroxy-3-methyl, o-Allylhydroxylamine, 2-
Butanamine, 3-methyl, Hexanal , 2-chloro, Hexanoic acid, 4-octyl ester, Pyrrolidine , 2,5-dimethyl-1-
nitroso, 3-Pentanone , dimethylhydrazone, 1-Pentanol, 2-ethyl, 3-Methyl-1,4-diazabicyclo[4.3.0]nonan-
2,5-dione, Pyrrolo[1.2-a]pyrazine-1,4-dione,hexahydro. Nerium olender (Alkaloids) was very highly active
6.800±0.24 mm. The results of anti-fungal activity produced by Neisseria gonorrhea showed that the volatile
compounds were highly effective to suppress the growth of Aspergillus flavus (6.800±0.24).

وصف الــ Tags لهذا الموضوع   Anti-Microbial, Neisseria gonorrhea, GC-MS, Secondary metabolites