Thalassemia is one of the most dangerous disease. It is an inherited of hemoglobin
production , in which there is partial or complete failure of the synthesis of goblin
chain .The samples were collected from patients whom consulted the "Thalassemia
Center" in the Babylon Hospital – Babylon Governorate – Iraq for the care and
treatment thalassemia patients during the period of January 2011 to May 2011 .
50(30male and 20 female ) subjects with beta thalassemia major were included
.Serum levels of Sodium, potassium ,Calcium ,Iron, Total Iron Binding Capacity , and
Ferritin were measured .The finding were compared with 40 (25male and 15 female)
matched healthy controls. A significant increase in levels of potassium, Calcium ,and
Iron (p<0.005) and ferittin (p<0.001). Non significant increase in the sodium and
total iron binding capacity levels were found in the patients when compared with
controls .It has been concluded that thalassemic patients presented multiple
abnormalities due to repeated transfusion , iron overload ,hepatitis ,cardiac and renal
dysfunction.