Protein Synthesis

?-oxidation
• B-oxidation of palmitate (C16:0) yields 106 molecules
of ATP
• C 16:0-CoA + 7 FAD + 7 NAD+ + 7 H 2 0 + 7 CoA?
8 acetyl-CoA + 7 FADH2 + 7 NADH + 7 H+
2.5 ATPs per NADH = 17.5
1.5 ATPs per FADH2 = 10.5
10 ATPs per acetyl-CoA = 80
Total = 108 ATPs
• 2 ATP equivalents (ATP?AMP + PPi, PPi?2 Pi)
consumed during activation of palmitate to acyl-CoA• Net yield = 106 ATPs
Acyl-CoA Dehydrogenase?-oxidation of
odd
chain fatty acids?-oxidation of unsaturated fatty acids
?-oxidation of fatty acids with even
numbered double bonds Import of acyl-CoA into mitochondria Import of acyl-CoA into mitochondria
?-oxidation
• B-oxidation of palmitate (C16:0) yields 106 molecules
of ATP
• C 16:0-CoA + 7 FAD + 7 NAD+ + 7 H 2 0 + 7 CoA?
8 acetyl-CoA + 7 FADH2 + 7 NADH + 7 H+
2.5 ATPs per NADH = 17.5
1.5 ATPs per FADH2 = 10.5
10 ATPs per acetyl-CoA = 80
Total = 108 ATPs
• 2 ATP equivalents (ATP?AMP + PPi, PPi?2 Pi)
consumed during activation of palmitate to acyl-CoA• Net yield = 106 ATPs
Acyl-CoA Dehydrogenase?-oxidation of
odd
chain fatty acids?-oxidation of unsaturated fatty acids
?-oxidation of fatty acids with even
numbered double bonds Import of acyl-CoA into mitochondria Import of acyl-CoA into mitochondria